In France, consistent with analysis by means of the Analgesia basis, 23.1 million other folks reside with persistent ache. Just a 3rd of them see their scenario enhance due to make stronger, particularly because of the loss of correct remedy. A heavy burden that burdens now not most effective people, but additionally society as a complete. To relieve it, we should make the battle towards persistent ache a significant nationwide motive.
Consider residing with consistent ache, daily, without a hope of reduction. For tens of millions of other folks in France, that is the truth of persistent ache, a time period that refers to habitual ache that lasts longer than 3 consecutive months and that has vital bodily, ethical and social penalties.
This invisible illness has an excessively vital affect at the high quality of lifestyles, and is a problem now not just for our well being device, but additionally for society as a complete, as a result of this nice burden isn’t with out financial penalties.
Authorized by means of the Ministry of Upper Training and Analysis, the Analgesia Basis, thru its French Observatory for Ache and Analgesics, performed a countrywide survey of eleven,940 other folks, consultant of the overall French grownup inhabitants, in early 2025 with the corporate OpinionVai.
The purpose used to be to evaluate the superiority of persistent ache in France, their characterization and repercussions on their high quality of lifestyles. Here is what you wish to have to bear in mind.
4 out of ten other folks in France are suffering from persistent ache
In contrast to acute ache, which serves as an alarm sign that allows the essential measures to be taken within the match of an match that poses a risk to the human frame (fracture, burn, lower, stab, and so on.), persistent ache is pointless. It has most effective damaging penalties for the affected person.
Very schematically, persistent ache is frequently the results of a so-called “peripheral” supply of ache, as it impacts the peripheral anxious device – this is, the portions of the anxious device which are out of doors the central anxious device, consisting of the mind and spinal wire.
A large number of painful alerts flooding the mind adjust its habits: it turns into extra delicate to them (we’re speaking about central sensitization), and their processing is now not carried out appropriately. On this scenario, ache modulation, which in most cases is going in the course of the so-called “descending” neurological pathways (from the mind to the outer edge), additionally does now not paintings. The task of all of the anxious device is constantly converting: the whole thing occurs as though as an alternative of dampening the reaction to painful alerts, the latter turns into extra intense.
Out of control intense acute ache, nerve injury as a consequence of surgical procedure or trauma, background nervousness or impaired sleep additionally consolidate this central sensitization. A number of pathophysiological mechanisms can provide an explanation for the incidence of those ache “diseases”.
Postoperative harm may cause neuropathic ache (because of disorder of the anxious device fairly than stimulation of ache receptors), central hyperexcitability with out glaring irritation or harm may cause fibromyalgia or irritable bowel syndrome. Chronic irritation, as in joint lesions (arthropathy) of inflammatory beginning or tendinopathy (painful tendon illnesses), additionally lowers the edge for activation of receptors for the ache message.
Symbol of the OFDA/Basis for Analgesia ache barometer. Creator supplied (no reuse)
Power ache has critical penalties for sufferers, because it impacts now not most effective their bodily and psychological talents, but additionally their skilled and circle of relatives lifestyles. To such an extent that a few of them, whose ache is refractory, i.e. immune to all remedies, occasionally get to the purpose of requesting assist in demise.
An research of information accumulated by means of the French Observatory for Ache and Analgesics presentations that during France, greater than 23 million French other folks, most commonly girls (57%), reside with ache, more often than not for no less than 3 months.
Symbol of the OFDA/Basis for Analgesia Ache Barometer. Creator supplied (no reuse)
At the podium of the most typical pains are pains of the musculoskeletal device, together with osteoarthritis or ache within the decrease again; more than a few complications, together with migraines; and belly ache, together with irritable bowel syndrome or endometriosis.
With a median age of 46, the 35-64 age crew represents 51% of the inhabitants affected by persistent ache. Virtually 36% are professionally inactive.
This persistent illness is a burden this is the entire higher as a result of it is extremely poorly handled: just a 3rd of sufferers say they’re happy with the remedy.
Loss of make stronger
Virtually each and every different affected person charges the depth in their ache as 7 or extra on a scale of one to ten, this is, serious persistent ache, and 44% have suffered from it for greater than 3 years.
All over the six months main as much as the find out about, lower than one in 3 sufferers noticed an development of their signs. Additionally, greater than a 3rd of the tested sufferers have reasonable to serious practical incapacity, and part state impaired bodily and psychological qualities.
Symbol of the OFDA/Basis for Analgesia Ache Barometer. Creator supplied (no reuse)
When requested about their care, most effective 37% of sufferers say they’re happy. One drawback is that to be had remedies are hardly ever explicit to the ache in query. They most often partly cut back the depth of the indicators, however they don’t all the time have a vital affect at the burden that this illness represents within the sufferers’ lives.
Paracetamol, anti inflammatory medicine and opioids (morphine and derivatives) are 3 varieties of medicine prescribed to regard persistent ache. An indication of inadequate reduction, 87% of sufferers document training self-medication to check out to relieve their struggling.
An important social value
Because of its prime incidence in society, persistent ache has an estimated value of a number of billion euros consistent with 12 months, if the commercial penalties of the lack of productiveness it reasons are added to the well being prices essential for its control.
A 2004 find out about estimated the typical overall annual prices consistent with affected person at greater than 30,000 euros. This determine highlights the numerous financial affect of this situation, which matches past its direct prices to the healthcare device.
Due to this fact, other folks affected by persistent ache are 5 instances much more likely to be out of labor than the overall inhabitants. As well as, the typical cumulative period of labor interruption for 45% of sufferers with persistent ache exceeds 4 months consistent with 12 months.

Power ache reasons a lot of interruptions in paintings. Olga Kazantseva/Shutterstock
Every other epidemiological find out about, performed in 2010, amongst greater than 15,000 adults in France, made it conceivable to evaluate the affect of ache on skilled eventualities and on using the well being care device. It presentations that sufferers affected by persistent ache are consulted two times as frequently as others.
Extrapolating that 12 months to the overall inhabitants, 72 million further consultations consistent with 12 months are because of persistent ache, representing an extra annual value estimated at €1.16 billion. This paper additionally discovered that absenteeism because of this ache then accounted for 48 million misplaced paintings days consistent with 12 months, nationally.
Searching for a “better life with” as an alternative of “without pain”
Analysis and remedy of a affected person affected by persistent ache calls for simultaneous attention of organic, mental and social elements, with no priori appearing the relative significance of every of them, consistent with the so-called “biopsychosocial” clinical style.
“It’s time for every patient to have access to a dignified care pathway, without wandering or abandonment,” underlines Audrey Aronique, president of the French-speaking Affiliation for Overcoming Ache (AFVD).
Handiest 4 out of ten sufferers get pleasure from multiprofessional handle their persistent ache. If, as we have now noticed, most effective 37% of sufferers say they’re happy with their care, this determine rises considerably when individuals are adopted by means of a construction specialised in persistent ache: then we achieve 47% happy.
Pride is decrease for positive pains reminiscent of fibromyalgia, endometriosis, cancer-related ache, and inflammatory or neuropathic ache.
Symbol of the OFDA/Basis for Analgesia Ache Barometer. Creator supplied (no reuse)
The healing objective for an individual affected by persistent ache isn’t whole remission or remedy of the illness. In persistent ache, atmosphere the objective of whole ache solution is frequently unrealistic and occasionally even counterproductive, frequently resulting in doubtlessly damaging escalations of remedy. This frequently leads to long-term prescription of opioid medicine (morphine or equivalents), even though they don’t seem to be advisable for all ache. With the danger of growing dependancy to those remedies.
Within the face of persistent ache, the objective of remedy is largely rehabilitative (residing higher along with your ache). The objective is to cut back ache to a suitable degree for the affected person and enhance the affected person’s practical talents and high quality of lifestyles. Rehabilitation is extremely person-centered, that means that the interventions and manner selected for every particular person rely on their objectives and personal tastes.
It will also be fascinating to inspire the promotion of scientifically confirmed remedies that don’t seem to be medicine, reminiscent of neuromodulation – a method that is composed of sending, the use of electrodes implanted as an example within the affected person’s spinal wire, electric alerts geared toward modulating ache alerts despatched to the mind.
“Digital therapies” accompanying the advance of “digital health” will also be fascinating. They make scientifically confirmed content material to be had, the use of packages that may be consulted on smartphones, in addition to complementary, psycho-physical approaches that allow higher ache control and cut back its detrimental day-to-day repercussions at the high quality of lifetime of sufferers: fatigue, detrimental feelings, insomnia, lowered morale, bodily inaction.
The country’s main motive for preventing the load of persistent ache
To be able to enhance the placement, it is vital for the government to deal with the subject of the battle towards persistent ache by means of mentioning it a “great national cause”. Awarding this designation would permit higher conversation about this major problem, in addition to make stronger and coordination of study efforts.
“The results of the Pain 2025 barometer require our national community to undertake a major health response,” says Dr Eric Serra, President of the French Society for the Find out about and Remedy of Ache (SFETD).
Amongst different objectives to be completed, we will have to point out the security of extra significant educating of ache drugs in clinical research, focused investment of nationwide analysis systems, concrete implementation of tasks that allow the aid of delays in get entry to to specialised care and the battle towards territorial or financial inequalities in get entry to to positive remedies.