In Colorado, from 2016 to 2020, 33 ladies who have been pregnant or had not too long ago given start died from unintended overdoses. That’s greater than died from conventional obstetric headaches like an infection, hypertension or bleeding blended.
Newer knowledge displays an encouraging turnaround. The selection of maternal overdose deaths dropped 60%, from 20 in 2022 to 8 in 2023. I believe one contributing issue may well be larger get entry to to naloxone for mothers and households around the state.
As a perinatal dependancy medication doctor, I concentrate on taking good care of pregnant other people and households impacted by way of substance use dysfunction. A part of the care I supply is prescribing or distributing naloxone without delay to sufferers and their members of the family. Naloxone is an over the counter drugs that reverses the results of opioid overdose.
On this video, the Substance Abuse and Psychological Well being Services and products Management explains how naloxone, an opioid overdose-reversal drugs, works within the frame.
I served as a member after which co-chair of the Colorado Maternal Mortality Assessment Committee from 2017 to 2023. The committee opinions each demise of an individual in Colorado that happens all through a being pregnant or inside twelve months of the top of a being pregnant. I for my part reviewed the information of Colorado moms who died from overdoses.
In Colorado, accidental overdose and suicide were the highest two reasons of maternal mortality each and every 12 months since 2016. Nationally, the main reason behind maternal mortality is overdose, adopted by way of murder after which suicide.
Nearly all overdose deaths happen in the neighborhood, out of doors of a scientific middle: in houses, vehicles and public puts. In virtually all cases, the overview committee made up our minds that if naloxone were provide, there was once a superb opportunity the mum would have survived.
Giving naloxone without delay to sufferers and households
In 2023, The Naloxone Challenge, a nonprofit, began distributing naloxone without delay to pregnant and postpartum mothers and their households sooner than leaving probably the most 48 birthing hospitals in Colorado. The distribution is thru a program known as the Maternal Overdose Issues Initiative, sometimes called MOMs. The initiative was once in direct reaction to the selection of ladies death from overdose all through being pregnant or inside a 12 months after being pregnant.
The Naloxone Challenge was once began in Colorado in 2021 by way of an emergency and dependancy medication doctor. The challenge distributes naloxone without delay to sufferers in Colorado sanatorium emergency rooms in danger for opioid overdose.
So far, The Naloxone Challenge has allotted greater than 2,500 naloxone kits to 107 hospitals to offer to sufferers around the state. The challenge additionally works to normalize the dialog about opioid overdose and prevention in well being care settings. It’s grown, and now it has chapters in 16 states.
Naloxone could make restoration conceivable
The American Society of Habit Drugs defines substance use dysfunction as “a treatable, chronic medical disease involving complex interactions among brain circuits, genetics, the environment and an individual’s life experiences.” Other people with the illness of dependancy can, and do, recuperate – however provided that they may be able to keep alive to obtain the improve and remedy they want.
Rachel Lambert, a recuperating heroin consumer, demonstrates tips on how to administer naloxone.
Michael S. Williamson/The Washington Put up by means of Getty Pictures
Analysis displays direct distribution of naloxone to other people, households and communities saves lives. Get right of entry to to naloxone offers other people, together with Colorado mothers, a literal 2nd likelihood at lifestyles.
Naloxone for greater than substance use dysfunction
Whilst other people with substance use dysfunction are on the perfect possibility for overdose, they’re no longer the one ones. In 2024 on my own, 1,603 other people died of unintended opioid overdoses in Colorado.
Prescription opioids, reminiscent of oxycodone, hydrocodone and morphine, are frequently prescribed after a surgical procedure, together with C-sections. Opioids like those taken at house, even with a prescription, is usually a supply of unintended overdose. For instance, an individual prescribed those drugs might take an excessive amount of immediately or have an surprising interplay with different medicines or alcohol.
Unintentional overdose additionally happens in other people the prescription was once no longer supposed for. That comes with youngsters who to find medicines of their houses. In Colorado, 17 youngsters died from opioid overdoses in 2024.
Lately, folks leaving the sanatorium with their new child are given naloxone and training. They know about protected garage and disposal of medicines, tips on how to acknowledge an opioid overdose, and tips on how to give naloxone in case of emergency. Nasal-spray naloxone, the most typical shape equipped by way of The Naloxone Challenge, is protected for every age, together with babies and little toddlers.
Naloxone as an ordinary of care
Taking good care of other people impacted by way of substance use dysfunction has satisfied me that naloxone has a spot in each house, faculty and place of work in our neighborhood.
Spotting and responding to opioid overdose, together with giving naloxone, is now an ordinary a part of Fundamental Lifestyles Strengthen coaching. Opioid overdose reversal is now observed as a vital, lifesaving talent related to CPR. Together with this talent in coaching empowers bystanders to interfere.

Justin, a player in a category on opioid overdose prevention, practices with naloxone on instructor Keith Allen.
Spencer Platt/Getty Pictures
For a few of my sufferers, receiving naloxone all through an overdose tournament gave them a possibility to hunt remedy and input long-term restoration from substance use. Opioid use dysfunction remedy contains evidence-based drugs for opioid use dysfunction, reminiscent of methadone, buprenorphine or naltrexone, residential or extensive outpatient remedy, particular person remedy and peer improve products and services, particularly techniques designed for pregnant and parenting mothers.
How those aspects of remedy come in combination in a person particular person’s adventure is exclusive. Up to I search to individualize remedy plans, naloxone is for everybody. It will probably construct a bridge between depression and hope — lifestyles and demise — and because the knowledge displays, it may well be part of saving Colorado mothers’ lives.